1)   H. Abe, T. Fukumoto, Y. Takeuchi, T. Harayama
Synthesis of Alternariol through an Intramolecular Biaryl Coupling Reaction Using Palladium Reagent

      Heterocycles, 74, 265-271 (2007).

2)   G. Serban, Y. Shigeta, H. Nishioka, H. Abe, Y. Takeuchi, T. Harayama

      Studies toward the Synthesis of Toddaquinoline by Intramolecular Cyclization

      Heterocycles, 71, 1623-1630 (2007).

3)   S. Takeda, H. Abe, Y. Takeuchi, T. Harayama   
Intramolecular Biaryl Coupling Reaction of Benzyl Benzoate and Phenyl Benzoate Derivatives, and Its Application to the Formal Synthesis of (-)-Steganone

      Tetrahedron, 63, 396-408 (2007).

4)   H. Nishioka, C. Nagura, H. Abe, Y. Takeuchi, T. Harayama

      Biaryl Coupling Reactions of 3-Methoxy-N-(2-iodophenyl)-N-methylbenzamide and 3-Methoxycarbonyl-N-(2-iodophenyl)-N-methylbenzamide Using Palladium Reagent

      Heterocycles, 70, 549-555 (2006).

5)   H. Abe, T. Fukumoto, M. Arai, Y. Takeuchi, T. Harayama

      Syntheses of Ulocladol

   Heterocycles, 69, 217-222 (2006).

6)   T. Harayama, A. Hori, H. Abe, Y. Takeuchi

      Regioselectivity in the Biaryl Coupling Reactions of 1-[(1,3-Benzodioxol-5-yl)methyl]-7- iodo-2,3-dihydroindole Using Palladium Reagent

      Heterocycles, 67, 385-390 (2006).

7)   T. Harayama, T. Sato, A. Hori, H. Abe, Y. Takeuchi

      Palladium-Assisted Biaryl Coupling Reaction of 1-(2-Iodobenzoyl)-1,2,3,4- Tetrahydroquinoline

      Heterocycles, 66, 527-530 (2005).

8)   T. Harayama, Y. Kawata, C. Nagura, T. Sato, T. Miyagoe, H. Abe, Y. Takeuchi

      Effect of Oxygen Substituents on the Pd-Assisted Biaryl Coupling Reaction of Benzanilides

      Tetrahedron Lett., 46, 6091-6094 (2005).

9)   Y. Takeuchi, M. Oshige, K. Azuma, H. Abe, T. Harayama

      Concise Synthesis of dl-Febrifugine

      Chem. Pharm. Bull., 53, 868-869 (2005).

10)  H. Abe, K. Nishioka, S. Takeda, M. Arai, Y. Takeuchi, T. Harayama

      Synthesis of Graphislactones A-D through a Palladium-Mediated Biaryl Coupling Reaction of Phenyl Benzoate Derivatives

      Tetrahedron Lett., 46, 3197-3200 (2005).

11)  H. Nishioka, Y. Shojiguchi, H. Abe, Y. Takeuchi, T. Harayama

      Intramolecular Pd-Catalyzed Biaryl Coupling Reaction of N-Aryl-2-Triflyloxybenzamides Using Pd(OAc)2, 1,3-Bis[diphenylphosphino]propane, Bu3P, and DBU

      Heterocycles, 64, 463-466 (2004).

12) T. Harayama, A. Hori, G. Serban, Y. Morikami, T. Matsumoto, H. Abe, Y. Takeuchi

      Concise Synthesis of Quinazoline Alkaloids, Luotonins A and B, and Rutaecarpine

      Tetrahedron, 60, 10645-10649 (2004).

13) T. Harayama, T. Sato, A. Hori, H. Abe, Y. Takeuchi

      Novel Synthesis of a New Skeletal Compound Benzonaphthazepine by Regioselective C-H Activation Utilizing the Intramolecular Coordination of an Amine to Pd

      Synthesis, 1446-1456 (2004).

14)  H. Abe, S. Takeda, T. Fujita, K. Nishioka, Y. Takeuchi, T. Harayama

      Enantioselective Construction of Biaryl Part in the Synthesis of Stegane Related Compounds

      Tetrahedron Lett., 45, 2327-2329 (2004).

15)  T. Harayama, A. Hori, H. Abe, Y. Takeuchi

      Concise Synthesis of Pyrrolophenanthridine Alkaloids Using a Pd-Mediated Biaryl Coupling Reaction with Regioselective C-H Activation via the Intramolecular Coordination of the Amine to Pd

      Tetrahedron, 60, 1611-1616 (2004).

16)  T. Harayama, Y. Morikami, A. Hori, H. Nishioka, H. Abe, Y. Takeuchi

      Concise Synthesis of 11H-Indolizino[1,2-b]quinolin-9-one by an Aryl-Aryl Coupling Reaction Using Pd Reagent

      Hetrocycles, 62, 803-806 (2004).

17) H. Abe, S. Takeda, Y. Takeuchi, T. Harayama

      An Attempt for Biaryl Coupling Reaction of Benzyl Benzoate Derivatives under Ullmann Conditions.

      Heterocycles, 61, 521-528 (2003).

18) T. Harayama, H. Toko, A. Hori, T. Miyagoe, T. Sato, H. Nishioka, H. Abe, Y. Takeuchi

      Synthetic Studies on Pyrrolophenanthridone Skeleton from 1-Benzoyl-7-iododihydroindole Derivatives Using Palladium-assisted Biaryl Coupling Reactions.

      Heterocycles, 61, 513-520 (2003).

19) T. Harayama, A. Hori, H. Abe, Y. Takeuchi

      Concise Synthesis of Pyrrolophenanthridine Alkaloids Using a Pd-catalyzed Biaryl Coupling Reaction with Regioselective C-H Activation.

      Heterocycles, 60, 2429-2434 (2003).

20) T. Harayama, Y. Sato, A. Hori, H. Abe, Y. Takeuchi

      Novel Synthesis of Naphthobenzazepins from N-Bromobenzylnaphthylamines by Regioselective C-H Activation Utilizing Intramolecular Coordination of an Amine to Pd.

      Synlett, 1141-1144 (2003).

21)  T. Harayama, Y. Morikami, Y. Shigeta, H. Abe, Y. Takeuchi

      A Convenient Synthesis of Luotonins A and B.

      Synlett, 847-848 (2003).

22)  T. Harayama, H. Toko, H. Nishioka, H. Abe, Y. Takeuchi

      Concise Synthesis of Tetrahydrophenanthridone by Palladium Reagent.

      Heterocycles, 59, 541-546 (2003).

23) Y. Takeuchi, K. Azuma, M. Oshige, H. Abe, H. Nishioka, K. Sasaki, T. Harayama

      Synthesis of Febrifugine Derivatives and a Solution to the Puzzle of the Structural Determination of Febrifugine.

      Tetrahedron, 59, 1639-1646 (2003).

24) T. Harayama, T. Sato, Y. Nakano, H. Abe, Y. Takeuchi

      Concise Synthesis of Fagaridine and Decarine, Phenolic Benzo[c]phenanthridine Alkaloids, Using the Palladium-assisted Biaryl Coupling Reaction.

      Heterocycles, 59, 293-302 (2003).

25)  Y. Takeuchi, N. Ueda, K. Uesugi, H. Abe, H. Nishioka, T. Harayama

      Convenient Synthesis of a Simple Coumarin from Salicylaldehyde and Wittig Reagent. IV: Improved Synthetic Method of Substituted Coumarins.

Heterocycles, 59, 217-224 (2003).

26)  T. Harayama, H. Toko, K. Kubota, H. Nishioka, H. Abe, Y. Takeuchi

      Studies on the Selective Intramolecular Biaryl Coupling Reaction of 6-Tryflyloxy-2-halobenzanilides Using a Palladium Reagent.

      Heterocycles, 58, 175-181 (2002).

27)  T. Harayama, A. Hori, Y. Nakano, T. Akiyama, H. Abe, Y. Takeuchi

      Aryl-aryl Coupling Reaction Catalyzed by a Palladium Reagent Prepared from Pd(OAc)2 and n-Bu3P.

      Heterocycles, 58, 159-164 (2002).

28)  H. Abe, T. Tsujino, K. Araki, Y. Takeuchi, T. Harayama

      Enantioselective Construction of Bicyclo[3.1.0]hexane Derivatives through Asymmetric Deprotonation of meso-Cyclic Ketones.

Tetrahedron: Asymmetry, 13, 1519-1527 (2002).

29)  A. Kawada, S. Takeda, K. Yamashita, H. Abe, T. Harayama

       Scandium (III) Trifluoromethanesulfonate Catalyzed Aromatic Nitration with Inorganic Nitrates and Acetic Anhydride.

       Chem. Pharm. Bull., 50, 1060-1065 (2002).

30)  Y. Takeuchi, K. Azuma, H. Abe, K. Sasaki, T. Harayama

       Re-revision of the StereoStructure of Piperidine Lactone, an Intermediate in the Synthesis of Febrifugine.

       Chem. Pharm. Bull., 50, 1011-1012 (2002).

31)  T. Harayama, T. Akiyama, Y. Nakano, H. Nishioka, H. Abe, Y. Takeuchi

       Aryl-Aryl Coupling Reaction Using a Novel and Highly Active Palladium Reagent Prepared from Pd(OAc)2, 1,3-Bis[diphenylphosphino]propane (DPPP), and Bu3P.

       Chem. Pharm. Bull., 50, 519-522 (2002).

32)  A. Kawada, K. Yasuda, H. Abe, T. Harayama

       Rare Earth Metal Trifluoromethanesulfonates Catalyzed Benzyl-Etherification.

       Chem. Pharm. Bull., 50, 380-383 (2002).

33) T. Harayama, T. Akiyama, Y. Nakano, K. Shibaike, H. Akamatsu, A. Hori, H. Abe, Y. Takeuchi

       Synthesis of Benzo[c]phenanthridine Alkaloids, Using a Novel Palladium-Phosphine Combination System - Pd(OAc)2, DPPP, and Bu3P.

       Synthesis, 237-241 (2002).

34)  H. Abe, T. Tsujino, D. Tsuchida, S. Kashino, Y. Takeuchi, T. Harayama

       Enantioselective Deprotonation of Cs-Symmetric Cyclohept-4-enone oxides.

       Heterocycles, 56, 503-508 (2002).

35)  H. Abe, A. Yamasaki, N. Koshiba, Y. Takeuchi, T. Harayama

       One-Pot Conversion of Allyl Alcohols into Selenochroman Derivatives.

       Chem. Pharm. Bull., 49, 1223-1225 (2001).

36)  Y. Takeuchi, M. Koike, K. Azuma, H. Nishioka, H. Abe, H.-S.Kim, Y. Wataya, Harayama

       Synthesis and Antimalarial Activity of Febrifugine Derivatives.

       Chem. Pharm. Bull., 49, 721-725 (2001).

37)  T. Harayama, T. Akiyama, H. Akamatsu, K. Kawano, H. Abe, Y. Takeuchi

       Total Synthesis of Benzo[c]phenanthridine Alkaloids, Chelerythrine and 12-Methoxydihydro-chelerythrine, by a Palladium-Assisted Internal Biaryl Coupling Reaction.

       Synthesis, 444-450 (2001).

38)  T. Harayama, H. Akamatsu, K. Okamura, T. Miyagoe, T. Akiyama, H. Abe, Y. Takeuchi

       Synthesis of Trisphaeridine and Norchelerythrine through Palladium-Catalyzed Aryl-Aryl Coupling Reactions.

       J. Chem. Soc. Perkin Trans. 1, 523-528 (2001).

39)  Y. Takeuchi, K. Azuma, K. Takakura, H. Abe, H.-S. Kim, Y. Wataya, T. Harayama

       Asymmetric Synthesis of (+)-Febrifugine and (+)-Isofebrifugine Using Yeast Reduction.

       Tetrahedron, 57, 1213-1218 (2001).

40)  T. Harayama, K. Katsuno, Y. Nishita, M. Fujii, H. Abe, Y. Takeuchi

       Revision of the Structure of a New Coumarin Isolated from Artemisia carviforia Wall.

       Heterocycles, 54, 319-328 (2001).

41)  Y. Takeuchi, K. Azuma, H. Abe, T. Harayama

       Reaction of N-Acylated Isofebrifugine with Acid.

       Heterocycles, 53, 2247-2252 (2000).

42)  Y. Takeuchi, K. Azuma, K. Takakura, H. Abe, T. Harayama

      Asymmetric Synthesis of Febrifugine and Isofebrifugine Using Yeast Reduction.

      Chem. Commun., 1643-1644 (2000).

43)  T. Harayama, H. Yasuda, T. Akiyama, Y. Takeuchi, H. Abe

      Synthesis of Arnottin I through a Palladium-Mediated Aryl-Aryl Coupling Reaction.

      Chem. Pharm. Bull., 48, 861-864 (2000).

44)  H. Abe, H. Fujii, A. Yamasaki, Y. Kinome, Y. Takeuchi, T. Harayama

      Preparation of alpha-Seleno-alpha, beta-unsaturated Nitroalkenes via a Sulfur-Selenium Exchange Reaction.

      Synth. Commun., 30, 543-549 (2000).

45)  H. Abe, H. Fujii, N. Koshiba, Y. Takeuchi, T. Harayama

      Preparation of Iodo-Induced 1,3-Oxathiane Compounds via Intramolecular Pummerer Rearrangement of 2-Benzylsulfinylbicyclo[2.2.1]hept-5-ene.

      Heterocycles, 52, 465-470 (2000).

46)  Y. Takeuchi, M. Hattori, H. Abe, T. Harayama

      Synthesis of dl-Febrifugine and dl-Isofebrifugine.

      Synthesis, 1814-1818 (1999).

47)  H. Abe, N. Koshiba, A. Yamasak, T. Harayama

      Conversion of Allyl Aryl Selenides into Selenochroman Derivatives.

      Heterocycles, 51, 2301-2304 (1999).

48)  Y. Takeuchi, Y. Nagao, K. Toma, Y. Yoshikawa, T. Akiyama, H. Nishioka, H. Abe, T. Harayama, S. Yamamoto

      Synthesis and Siderophore Activity of Vibrioferrin and Its Diastereomeric Isomer.

      Chem. Pharm. Bull., 47, 1284-1287 (1999).

49)  Y. Takeuchi, S. Tokuda, T. Takagi, M. Koike, H. Abe, T. Harayama, Y. Shibata, H.-S. Kim, Y. Wataya

      Synthesis and Antimalarial Activity of dl-Deoxyfebrifugine.

      Heterocycles, 51, 1869-1875 (1999).

50)  Y. Takeuchi, H. Abe, T. Harayama

      Total Synthesis of dl-Febrifugine and dl-Isofebrifugine.

      Chem. Pharm. Bull., 47, 905-906 (1999).

51)  H. Abe, D. Tsuchida, S. Kashino, Y. Takeuchi, T. Harayama

      The Diels-Alder Reaction Using a Vinyl Sulfoxide Activated by the Participation of a Neighboring Epoxide Group.

      Chem. Pharm. Bull., 47, 833-837 (1999).

52)  H. Abe, K. Shibaike, H. Fujii, D. Tsuchida, T. Akiyama, T. Harayama

      1,3-Oxathiane Ring Formation through Intramolecular Pummerer Reaction of Alkyl ortho-Hydroxymethylphenyl Sulfoxides.

      Heterocycles, 50, 291-298 (1999).

53) H. Abe, A. Yamasaki, T. Harayama

      Direct Conversion of a Benzylic Hydroxy Group into a Selenenyl Group Using the Phenyl Trimethylsilyl Selenide-Aluminum Bromide Combination.

      Chem. Pharm. Bull., 46, 1311-1313 (1998).

54) H. Abe, H. Fujii, C. Masunari, J. Itani, S. Kashino, K. Shibaike, T. Harayama

      Construction of 1,3-Oxathiane Ring through Pummerer Reaction of gamma,delta-Unsaturated Sulfinyl Compounds.

      Chem. Pharm. Bull., 45, 778-785 (1997).

55) H. Abe, A. Yamasaki, H. Fujii, T. Harayama

      Convenient Transformation of Benzyl Alcohol into Its Corresponding Selenide Using the Selenolate Anion-Aluminum Chloride Combination System.

      Chem. Pharm. Bull., 44, 2223-2226 (1996).

56)  H. Abe, J. Itani, C. Masunari, S. Kashino, T. Harayama

      Intramolecular Pummerer Reaction of gamma,delta-Unsaturated Sulfinyl Compounds.

      J. Chem. Soc., Chem. Commun., 1197-1198 (1995).

57)  K. Fuji, K. Tanaka, H. Abe, K. Matsumoto, T. Harayama, A. Ikeda, T. Taga, Y. Miwa, M. Node

      Diastereoselective Diels-Alder Cycloadditions with Chiral 1-(Alkylsulfinyl)-2-nitroalkenes.

       J. Org. Chem., 59, 2211-2218 (1994).

58)  M. Node, A. Itoh, K. Nishide, H. Abe, T. Kawabata, Y. Masaki, K. Fuji

      Preparation of Nitroalkenes: Substitution Reaction via Addition-Elimination Using b-Nitrovinyl Sulfoxides.

      Synthesis, 1119-1124 (1992).

59)  K. Fuji, K. Tanaka, H. Abe, K. Matsumoto, T. Taga, Y. Miwa

      Diastereoselective Diels-Alder Reactions with Chiral Sulfinyl Derivatives as Dienophiles under High Pressure.

      Tetrahedron: Asymmetry, 3, 609-612 (1992).

60)  K. Fuji, K. Tanaka, H. Abe, A. Itoh, M. Node, T. Taga, Y. Miwa, M. Shiro

      Enantioselective Construction of Highly Functionalized Bicyclo[4.3.0] System through Diels-Alder Cycloaddition.

      Tetrahedron: Asymmetry, 2, 1319-1327 (1991).

61)  K. Fuji, K. Tanaka, H. Abe, A. Itoh, M. Node, T. Taga, Y. Miwa, M. Shiro

      Asymmetric Diels-Alder Cycloaddition with Chiral 1-Alkylsulfinyl-2-nitroalkenes.

      Tetrahedron: Asymmetry, 2, 179-182 (1991).

62)  K. Fuji, M. Node, H. Abe, A. Itoh, Y. Masaki, M. Shiro

      Addition-Elimination Strategy for Asymmetric Induction: A Chiral Sulfoxide as a Leaving Group.

      Tetrahedron Lett., 31, 2419-2422 (1990).

2.総説

1) 阿部仁

      有機セレン化合物の特性を利用する新しい反応

      薬学雑誌, 123, 423-430 (2003).

3.著書

1 日本薬学会編「スタンダード薬学シリーズ・化学系薬学(演習編)」東京化学同人

  (2007). (共著)

4.その他

1)  阿部仁

 次世代抗菌剤の開発に向けて:プラテンシマイシンの合成研究

 ファルマシア43 (10), 1004-1005 (2007).